FG-5893

• Description :

  FG-5893 is a 5-HT1A receptor agonist and a 5-HT2 receptor antagonist. FG-5893 has anxiolytic effect[1][2].

• CAS Number :

  [150527-23-4]

• UNSPSC :

  12352005

• Target :

  5-HT Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/fg-5893.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(OC)C1=CC=CN=C1N2CCN(CC2)CCCC(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F

• Molecular Formula :

  C27H29F2N3O2

• Molecular Weight :

  465.53

• References & Citations :

  [1]Gunnar Andersson, et al. Effects of FG 5893, a new compound with 5-HT1A receptor agonistic and 5-HT2 receptor antagonistic properties, on male rat sexual behavior. European Journal of Pharmacology. Volume 255, Issues 1–3, 1 April 1994, Pages 131-137.|[2]Albinsson A, et al. Preclinical pharmacology of FG5893: a potential anxiolytic drug with high affinity for both 5-HT1A and 5-HT2A receptors. Eur J Pharmacol. 1994 Aug 22;261 (3) :285-94.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  5-HT1 Receptor