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Citreamicin alpha

CAT: 0804-HY-117845Size: 1 EachDry Ice: NoHazardous: No
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Description
Citreamicin alpha (LL-E 19085-alpha) is an antibiotic whose in vitro antimicrobial activity against 429 clinical isolates of Gram-positive cocci has been tested by the agar dilution method. These microorganisms included 313 strains of Staphylococci and 116 strains of Streptococci. The in vitro activity of Citreamicin alpha was compared with that of ampicillin, amoxicillin, ceftriaxone, erythromycin, and vancomycin. For Staphylococci, the MIC values of Citreamicin alpha ranged from 0.12-4.0 μg/ml, and for Streptococcus pyogenes of the genus Streptococcus, it was 0.03-0.12 μg/ml. However, enterococci were relatively resistant, requiring 2.0 μg/ml of the agent to inhibit 64% of the 62 tested strains. The in vitro activity of this antibiotic was much better than that of ampicillin, amoxicillin, ceftriaxone, and erythromycin, but comparable or slightly inferior to that of vancomycin.
CAS Number
122535-63-1
Product Name Alternative
LL-E19085α
UNSPSC
12352005
Target
Antibiotic; Bacterial
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/citreamicin-alpha.html
Smiles
O=C1C(OC2=CC(OC)=C(C=C23)OC)=C(C(C4=C5C(O)=C(C(N6C(C)(C7)OC(C6(COC(CC(C)C)=O)C)=O)=O)C7=CC5=CC=C41)=O)C3=O
Molecular Formula
C36H31NO12
Molecular Weight
669.63
References & Citations
[1]Antibacterial activity of citreamicin-alpha (LL-E 19085 alpha) against gram-positive cocci
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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