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BTK-IN-37

CAT: 0804-HY-159589Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-159589Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BTK-IN-37 (compound 8d) is a BTK inhibitor that can induce apoptosis in cancer cells. BTK-IN-37 targets BTK with Ki and IC50 of 5.07 nM and 3.6 nM, respectively. BTK-IN-37 can also selectively induce enrichment of genes involved in necroptosis and pyroptosis[1].
UNSPSC
12352005
Target
Apoptosis; Btk
Type
Reference compound
Related Pathways
Apoptosis; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/btk-in-37.html
Smiles
O=C(C1=CN=C(S(=O)(C)=O)N=C1N2CC(N3N=C(C4=CC=C(OC5=CC=CC=C5)C=C4)C6=C(N)N=CN=C63)CCC2)NC
Molecular Formula
C29H29N9O4S
Molecular Weight
599.66
References & Citations
[1]Exploring 2-Sulfonylpyrimidine Warheads as Acrylamide Surrogates for Targeted Covalent Inhibition: A BTK Story
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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