Isosorbide dinitrate-13C6

CAT: 0804-HY-B1409SSize: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-B1409SSize:1 mg
Selected
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Isosorbide dinitrate-13C6 is the 13C labeled Isosorbide dinitrate[1]. Isosorbide dinitrate (ISDN) is an NO donor that prevents LV remodeling and degradation of cardiac function following myocardial infarction (MI) [2].
Product Name Alternative
ISDN-13C6
UNSPSC
12352005
Target
NO Synthase
Type
Isotope-Labeled Compounds
Related Pathways
Immunology/Inflammation
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/isosorbide-dinitrate-13c6.html
Solubility
10 mM in DMSO
Smiles
[H][13C@]([13C@@H]([13CH2]O1)O[N+]([O-])=O)(O[13CH2]2)[13C@@]1([H])[13C@H]2O[N+]([O-])=O
Molecular Formula
13C6H8N2O8
Molecular Weight
242.09
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Wang X , et al. Intratracheal administration of isosorbide dinitrate improves pulmonary artery pressure and ventricular remodeling in a rat model of heart failure following myocardial infarction. Exp Ther Med. 2017 Aug;14 (2) :1399-1408.|[3]Zhao X, et al. Cardioprotective Effect of Isosorbide Dinitrate Postconditioning Against Rat Myocardial Ischemia-Reperfusion Injury In Vivo. Med Sci Monit. 2019 Mar 225:1629-1636.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

Popular Products