Isosorbide

• Description :

  Isosorbide (D-Isosorbide), an orally active vasodilating agent that can be used for the research of heart failure and angina (chest pain) . Isosorbide is also an oral hyperosmotic diuretic[1][2].

• Product Name Alternative :

  D-Isosorbide; Dianhydro-D-glucitol

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Others

• Type :

  Reference compound

• Related Pathways :

  Others

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Metabolic Disease; Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/Isosorbide.html

• Purity :

  99.22

• Solubility :

  DMSO : ≥ 100 mg/mL|H2O : ≥ 100 mg/mL

• Smiles :

  O[C@H]1[C@]2([H])[C@]([C@@H](O)CO2)([H])OC1

• Molecular Formula :

  C6H10O4

• Molecular Weight :

  146.14

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Rose M, et, al. Isosorbide as a renewable platform chemical for versatile applications--quo vadis? ChemSusChem. 2012 Jan 9;5 (1) :167-76.|[2]Nozawa I, et, al. Efficacy of long-term administration of isosorbide for Ménière's disease. ORL J Otorhinolaryngol Relat Spec. May-Jun 1995;57 (3) :135-40.|[3]Newman RA, et, al. Gallium nitrate (NSC-15200) induced toxicity in the rat: a pharmacologic, histopathologic and microanalytical investigation. Cancer. 1979 Nov;44 (5) :1728-40.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  Launched

• CAS Number :

  [652-67-5]