Products for Research Use Only
RegisterLogin

JNJ 2408068

CAT: 0804-HY-11098-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-11098-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
JNJ 2408068 is a potent RSV (respiratory syncytial virus) inhibitor. JNJ 2408068 significantly inhibits replication of RSV A and B subtypes in the lungs of cotton rats without any evidence of toxicity. The minimum protective dose of JNJ 2408068 appears to be approximately 0.39 mg/kg[1].
CAS Number
317846-22-3
Product Name Alternative
R170591
UNSPSC
12352005
Target
RSV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/jnj-2408068.html
Purity
96.57
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC1=CC=C(C)N=C1CN2C3=CC=CC(C)=C3N=C2NC4CCN(CCN)CC4
Molecular Formula
C22H30N6O
Molecular Weight
394.51
References & Citations
[1]Wyde PR, et al. Short duration aerosols of JNJ 2408068 (R170591) administered prophylactically or therapeutically protect cotton rats from experimental respiratory syncytial virus infection. Antiviral Res. 2003 Nov;60 (3) :221-31.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

Jnj-2408068
CAS Number317846-22-3
PubChem CID511013
IUPAC Name2-[[2-[[1-(2-aminoethyl)piperidin-4-yl]amino]-4-methylbenzimidazol-1-yl]methyl]-6-methylpyridin-3-ol
Molecular FormulaC22H30N6O
Molecular Weight394.5
XLogP2.4
Topological Polar Surface Area92.2
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Heavy Atom Count29
Formal Charge0
Complexity514
SMILES
CC1=C2C(=CC=C1)N(C(=N2)NC3CCN(CC3)CCN)CC4=C(C=CC(=N4)C)O
InChI
InChI=1S/C22H30N6O/c1-15-4-3-5-19-21(15)26-22(25-17-8-11-27(12-9-17)13-10-23)28(19)14-18-20(29)7-6-16(2)24-18/h3-7,17,29H,8-14,23H2,1-2H3,(H,25,26)
InChIKey
RDQSNNMSDOHAPG-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Jnj-2408068
CAS: 317846-22-3
CID: 511013
Formula: C22H30N6O
MW: 394.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight394.5
XLogP32.4
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Exact Mass394.24810960
Monoisotopic Mass394.24810960
Topological Polar Surface Area92.2 Ų
Heavy Atom Count29
Formal Charge0
Complexity514
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-P991172JNJ-70218902
HY-107139-01JNJ-10229570
HY-123481-01JNJ-42253432
HY-134188-01JNJ-54717793
HY-14450-01JNJ-31020028
HY-12190-01JNJ-5207852
HY-113751-01JNJ-39393406
HY-132895JNJ-67569762
HY-118424-01JNJ-55511118
HY-110132-01JNJ-27141491

Alternative Products

CatalogName
T27668-01JNJ-2408068

Popular Products