JNJ-31020028

JNJ-31020028

• CAS Number: 1094873-14-9
• UNSPSC Description: JNJ-31020028 is a selective and brain penetrant antagonist of neuropeptide Y Y2 receptor with pIC50 values of 8.07 and 8.22 for human and rat Y2 receptor, respectively. JNJ-31020028 can be used for the research of nervous disease[1].
• Target Antigen: Neuropeptide Y Receptor
• Type: Reference compound
• Related Pathways: GPCR/G Protein;Neuronal Signaling
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease; Endocrinology
• Assay Protocol: https://www.medchemexpress.com/JNJ-31020028.html
• Solubility: DMSO : 21.5 mg/mL (ultrasonic;warming)
• Smiles: O=C(N(CC)CC)C(N1CCN(C2=CC=C(NC(C3=C(C4=CC=CN=C4)C=CC=C3)=O)C=C2F)CC1)C5=CC=CC=C5
• Molecular Weight: 565.68
• References & Citations: [1]Shoblock JR, et al. In vitro and in vivo characterization of JNJ-31020028 (N-(4-{4-[2-(diethylamino)-2-oxo-1-phenylethyl]piperazin-1-yl}-3-fluorophenyl)-2-pyridin-3-ylbenzamide), a selective brain penetrant small molecule antagonist of the neuropeptide Y Y(2) receptor. Psychopharmacology (Berl). 2010 Feb;208(2):265-77.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported