DBCO-PEG3-C1-acid

DBCO-PEG3-C1-acid

• CAS Number: 2249926-65-4
• UNSPSC Description: DBCO-PEG3-C1-acid is an antibody–drug conjugate (ADC) linker, which is used as a reaction handle for strain-promoted azide-alkyne click reaction[1].
• Target Antigen: ADC Linker
• Type: Reference compound
• Related Pathways: Antibody-drug Conjugate/ADC Related
• Applications: Cancer-programmed cell death
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/dbco-peg3-c1-acid.html
• Smiles: O=C(COCCOCCOCCNC(CCC(N1C2=C(C#CC3=C(C1)C=CC=C3)C=CC=C2)=O)=O)O
• Molecular Weight: 494.54
• References & Citations: [1]Anami Y, et al. Glutamic acid-valine-citrulline linkers ensure stability and efficacy of antibody-drug conjugates in mice. Nat Commun. 2018 Jun 28;9(1):2512.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported