DBCO-PEG3-C1-acid

• UNSPSC Description:

  DBCO-PEG3-C1-acid is an antibody–drug conjugate (ADC) linker, which is used as a reaction handle for strain-promoted azide-alkyne click reaction[1].

• Target Antigen:

  ADC Linker

• Type:

  Reference compound

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/dbco-peg3-c1-acid.html

• Smiles:

  O=C(COCCOCCOCCNC(CCC(N1C2=C(C#CC3=C(C1)C=CC=C3)C=CC=C2)=O)=O)O

• Molecular Weight:

  494.54

• References & Citations:

  [1]Anami Y, et al. Glutamic acid-valine-citrulline linkers ensure stability and efficacy of antibody-drug conjugates in mice. Nat Commun. 2018 Jun 28;9(1):2512.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2249926-65-4