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DBCO-PEG3-C1-acid

CAT: 0804-HY-164209Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-164209Size:1 Each
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Description
DBCO-PEG3-C1-acid is an antibody–drug conjugate (ADC) linker, which is used as a reaction handle for strain-promoted azide-alkyne click reaction[1].
CAS Number
2249926-65-4
UNSPSC
12352005
Target
ADC Linker
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/dbco-peg3-c1-acid.html
Smiles
O=C(COCCOCCOCCNC(CCC(N1C2=C(C#CC3=C(C1)C=CC=C3)C=CC=C2)=O)=O)O
Molecular Formula
C27H30N2O7
Molecular Weight
494.54
References & Citations
[1]Anami Y, et al. Glutamic acid-valine-citrulline linkers ensure stability and efficacy of antibody-drug conjugates in mice. Nat Commun. 2018 Jun 28;9 (1) :2512.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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