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DBCO-PEG3-amine

CAT: 0804-HY-134714Size: 50 mgDry Ice: NoHazardous: No
CAT#:0804-HY-134714Size:50 mg
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Description
DBCO-PEG3-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-PEG3-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
CAS Number
[2093409-57-3]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dbco-peg3-amine.html
Purity
99.99
Solubility
10 mM in DMSO
Smiles
NCCOCCOCCOCCNC(CCC(N1C2=C(C#CC3=C(C1)C=CC=C3)C=CC=C2)=O)=O
Molecular Formula
C27H33N3O5
Molecular Weight
479.57
Precautions
H302, H315, H319, H335
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers

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