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Catestatin (TFA)

CAT: 0804-HY-P1271A-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P1271A-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Catestatin TFA is a 21-amino acid residue, cationic and hydrophobic peptide. Catestatin TFA is an endogenous peptide that regulates cardiac function and blood pressure[1]. Catestatin TFA is a non-competitive nicotinic antagonist acting through nicotinic acetylcholine receptors (nAChRs) to inhibit catecholamine release[2].
UNSPSC
12352209
Target
NAChR
Type
Peptides
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/catestatin-tfa.html
Purity
99.07
Solubility
H2O : 20 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C([C@@H](N)CCCNC(N)=N)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(NCC(N[C@H](C(N[C@H](C(NCC(N1[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CC(C)C)=O)CCC(N)=O)=O)CC(C)C)=O)=O)CCC1)=O)=O)CCCNC(N)=N)=O)CC2=CC=CC=C2)=O)=O)CC3=CC=C(O)C=C3)=O)=O)CCCNC(N)=N)=O)C)=O)CCCNC(N)=N)=O)CC4=CC=CC=C4)=O)CO)=O)CC(C)C)=O)CCCNC(N)=N)=O)CCSC)=O)CO.OC(C(F)(F)F)=O
Molecular Formula
C109H174F3N37O28S
Molecular Weight
2539.84
References & Citations
[1]Nitish R Mahapatra. Catestatin Is a Novel Endogenous Peptide That Regulates Cardiac Function and Blood Pressure. Cardiovasc Res. 2008 Dec 1;80 (3) :330-8.|[2]Sebastian Kraszewski, et al. A Molecular Dynamics Study of Catestatin Docked on Nicotinic Acetylcholine Receptors to Identify Amino Acids Potentially Involved in the Binding of Chromogranin A Fragments. Phys Chem Chem Phys. 2015 Jul 14;17 (26) :17454-60.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported

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