N-Desmethyl Zolmitriptan
CAT:
804-HY-W740014
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
N-Desmethyl Zolmitriptan
- CAS Number: 139264-35-0
- UNSPSC Description: N-Desmethyl Zolmitriptan (183C91; DZT) is the active metabolite of the serotonin (5-HT) receptor subtype 5-HT1B and 5-HT1D agonist Zolmitriptan (HY-B0229). N-Desmethyl Zolmitriptan (183C91; DZT) is an agonist of 5-HT1B receptors and induces constriction in isolated human cerebral arteries (EC50=100 nM).
- Target Antigen: 5-HT Receptor
- Type: Reference compound
- Related Pathways: GPCR/G Protein;Neuronal Signaling
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/n-desmethyl-zolmitriptan.html
- Smiles: CNCCC1=CNC2=C1C=C(C[C@@H](CO3)NC3=O)C=C2
- Molecular Weight: 273.33
- References & Citations: [1]Patel, et al. Systematic evaluation of matrix effect and cross-talk-free method for simultaneous determination of zolmitriptan and N-desmethyl zolmitriptan in human plasma: A sensitive LC-MS/MS method validation and its application to a clinical pharmacokinetic study. Biomed. Chromatogr. 30(3), 447-458 (2016).
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported