GNE-8324

CAT: 0804-HY-107498-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-107498-01Size:1 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
GNE-8324 is a selective GluN2A positive allosteric modulator. GNE-8324 selectively enhances NMDA receptor (NMDAR) -mediated synaptic responses in inhibitory but not excitatory neurons[1].
CAS Number
[1698901-76-6]
UNSPSC
12352005
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/gne-8324.html
Purity
98.88
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1C=C(CN(C2=CC=C(F)C=C2)CC)N=C3N1C(CCC4)=C4S3
Molecular Formula
C18H18FN3OS
Molecular Weight
343.42
References & Citations
[1]Lulu Yao, et al. Higher ambient synaptic glutamate at inhibitory versus excitatory neurons differentially impacts NMDA receptor activity. Nat Commun. 2018 Oct 1;9 (1) :4000.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NMDA Receptor

Related Products

CatalogName
HY-148238GNE-2256
HY-15883-01GNE-900
HY-18163-01GNE-7915
HY-149026-01GNE-064
HY-15766-01GNE-617
HY-175448GNE-1567
HY-150289-01GNE-235
HY-107986-01GNE-6776
HY-141551-01GNE-274
HY-107409-01GNE 5729

Alternative Products

CatalogName
BUP13927-01GNE-8324
400606-01GNE
DF4690-01GNE Antibody
G766100GNE 7915
bs-6546C-01GNE-617
TRC-G766000-5MGGNE-0877
TRC-D447825-2.5MGGNE-781
BUP12329-01GNE-375
BUP07936-01GNE-9815
BUP08046-01GNE-490

Popular Products