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GW 590735

CAT: 0804-HY-106278-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-106278-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GW 590735 is a potent and selective PPARα agonist. GW 590735 showsEC50=4 nM on PPARα and at least 500-fold selectivity versus PPARδ and PPARγ. GW 590735 can be used for the research of dyslipidemia[1].
CAS Number
343321-96-0
UNSPSC
12352005
Target
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/gw-590735.html
Purity
99.44
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
OC(C(C)(C)OC(C=C1)=CC=C1CNC(C2=C(C)N=C(C3=CC=C(C(F)(F)F)C=C3)S2)=O)=O
Molecular Formula
C23H21F3N2O4S
Molecular Weight
478.48
References & Citations
[1]Sierra ML, et al. Substituted 2-[ (4-aminomethyl) phenoxy]-2-methylpropionic acid PPARalpha agonists. 1. Discovery of a novel series of potent HDLc raising agents. J Med Chem. 2007;50 (4) :685-695.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
Phase 2

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