GW-117

• Description:

  GW-117 is a 5-HT2C receptor antagonist and a melatonin (MT1/MT2) receptor agonist. GW-117 shows antidepressant-like and anxiolytic-like effects[1].

• UNSPSC:

  12352005

• Target:

  5-HT Receptor; Isotope-Labeled Compounds; Melatonin Receptor

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling; Others

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Smiles:

  CC(NCCC1=CC=CC2=C1C=C(OC([2H])([2H])[2H])C(Cl)=C2)=O

• Molecular Formula:

  C15H13D3ClNO2

• Molecular Weight:

  280.76

• References & Citations:

  [1]Gao N, et al. GW117: A novel serotonin (5-HT2C) receptor antagonist and melatonin (MT1 /MT2) receptor agonist with potential antidepressant-like activity in rodents. CNS Neurosci Ther. 2021 Jun;27 (6) :702-713.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported

• Isoform:

  5-HT2 Receptor

• CAS Number:

  [2260629-83-0]