GW-117

• Description :

  GW-117 is a 5-HT2C receptor antagonist and a melatonin (MT1/MT2) receptor agonist. GW-117 shows antidepressant-like and anxiolytic-like effects[1].

• UNSPSC :

  12352005

• Target :

  5-HT Receptor; Isotope-Labeled Compounds; Melatonin Receptor

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling; Others

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Smiles :

  CC(NCCC1=CC=CC2=C1C=C(OC([2H])([2H])[2H])C(Cl)=C2)=O

• Molecular Formula :

  C15H13D3ClNO2

• Molecular Weight :

  280.76

• References & Citations :

  [1]Gao N, et al. GW117: A novel serotonin (5-HT2C) receptor antagonist and melatonin (MT1 /MT2) receptor agonist with potential antidepressant-like activity in rodents. CNS Neurosci Ther. 2021 Jun;27 (6) :702-713.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported

• Isoform :

  5-HT2 Receptor

• CAS Number :

  [2260629-83-0]