GW-9820

• Description:

  GW9820 is PPARα and PPARγ activator (EC50s: 0.37 μM for PPARα; 0.288 μM for PPARγ) . GW9820 increases CLA-1. GW9820 can be used in the research of atherosclerosis[1].

• UNSPSC:

  12352005

• Target:

  PPAR

• Related Pathways:

  Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

• Field of Research:

  Cardiovascular Disease

• Smiles:

  CC(C)(OC1=CC=C(CCN(C(NC2=CC=C(F)C=C2)=O)CCCCCCC)C=C1)C(O)=O

• Molecular Formula:

  C26H35FN2O4

• Molecular Weight:

  458.57

• References & Citations:

  [1]Chinetti G, et al. CLA-1/SR-BI is expressed in atherosclerotic lesion macrophages and regulated by activators of peroxisome proliferator-activated receptors. Circulation. 2000 May 23;101 (20) :2411-7.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  PPARα; PPARγ

• CAS Number:

  [195131-60-3]