5-Hydroxy-2'-deoxyuridine

• Product Name Alternative:

  5-OHdU

• UNSPSC Description:

  5-Hydroxy-2'-deoxyuridine (5-OHdU) is a major stable oxidation product of 2'-Deoxycytidine. 5-Hydroxy-2'-deoxyuridine can be incorporated into DNA in vitro by DNA polymerase[1].

• Target Antigen:

  Endogenous Metabolite

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/5-hydroxy-2-deoxyuridine.html

• Purity:

  99.77

• Solubility:

  DMSO : 33.33 mg/mL (ultrasonic)|H2O : 10 mg/mL (ultrasonic)

• Smiles:

  O[C@H]1C[C@H](N2C(NC(C(O)=C2)=O)=O)O[C@@H]1CO

• Molecular Weight:

  244.20

• References & Citations:

  [1]Purmal AA, et al. Major oxidative products of cytosine, 5-hydroxycytosine and 5-hydroxyuracil, exhibit sequence context-dependent mispairing in vitro. Nucleic Acids Res. 1994 Jan 11;22(1):72-8.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  5168-36-5