5-Chloro-2'-deoxyuridine

• UNSPSC Description:

  5-Chloro-2'-deoxyuridine, a thymine analog, is to study the potential of hypochlorous acid damage to DNA and DNA precursors.

• Target Antigen:

  Nucleoside Antimetabolite/Analog

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/5-Chloro-2_acute_-deoxyuridine.html

• Purity:

  99.96

• Solubility:

  DMSO : 250 mg/mL (ultrasonic)

• Smiles:

  OC[C@@H]1[C@@H](O)C[C@H](N2C(NC(C(Cl)=C2)=O)=O)O1

• Molecular Weight:

  262.649

• References & Citations:

  [1]Kim CH, et al. Polymerase incorporation and miscoding properties of 5-chlorouracil. Chem Res Toxicol. 2010 Apr 19;23(4):740-8.|[2]Yuan CJ, et al. Extended access methamphetamine decreases immature neurons in the hippocampus which results from loss and altered development of neural progenitors without altered dynamics of the S-phase of the cell cycle. Pharmacol Biochem Behav. 2011 Nov;100(1):98-108.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  50-90-8