Duocarmycin GA
CAT:
804-HY-128873-02
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Duocarmycin GA
- CAS Number: 1613286-59-1
- UNSPSC Description: Duocarmycin GA is an antibody agent conjugates (ADCs) toxin. Duocarmycin is a DNA alkylating agent that binds in the minor groove. Duocarmycin GA can be used against multi-agent resistant cell lines.
- Target Antigen: ADC Cytotoxin; DNA Alkylator/Crosslinker
- Type: ADC Related
- Related Pathways: Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/duocarmycin-ga.html
- Purity: 99.78
- Solubility: 10 mM in DMSO
- Smiles: O=C(NC1=CC2=C(C=C1)C=C(C(N3C[C@@H](CCl)C4=C3C=C(O)C5=CC=CC=C45)=O)N2)CN(C)C
- Molecular Weight: 476.95
- References & Citations: [1]Searcey M. Duocarmycins--natures prodrugs? Curr Pharm Des. 2002;8(15):1375-89.
- Shipping Conditions: Blue Ice
- Storage Conditions: -20°C (Powder, protect from light, stored under nitrogen)
- Clinical Information: No Development Reported