CHK-336

• UNSPSC Description:

  CHK-336 (Example 1) is an orally active LDHA inhibitor (IC50[1].

• Target Antigen:

  Lactate Dehydrogenase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/chk-336.html

• Solubility:

  DMSO : ≥ 130 mg/mL

• Smiles:

  O=C(C1=CSC(N2N=C(C(CC3=CC=C(S(=O)(N)=O)C(F)=C3)=C2CC4CC4)C5=CC=C(F)C=C5)=N1)O

• Molecular Weight:

  530.57

• References & Citations:

  [1]David Andrew Powell, et al. Substituted pyrazolyl compounds and methods of use thereof. Patent WO2021234547A1.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  Phase 1

• CAS Number:

  2743436-86-2