Caspase 3/7 Activity Detection Substrate for Flow Cytometry

• Detection Method:

  Fluorometric method; Flow cytometry

• Assay Principle:

  The Caspase 3/7 Substrates (Green) are based on novel fluorogenic DNA dyes that have been coupled to the caspase 3/7 recognition sequence (DEVD), which is both non-fluorescent and nonfunctional as a DNA dye.When it rapidly crosses cell membranes to enter the cytoplasm and cleaved by caspase 3/7 to form a high-affinity DNA dye that stains the nucleus bright green. Thus, the Caspase 3/7 substrates allow detection of caspase 3/7 activity and visualization of apoptotic nuclear morphology simultaneously.

• Sample Type:

  Cell samples

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  This product can be stored at 2~8°C for 1 year in the dark.

• Citation 01:

  https://pmc.ncbi.nlm.nih.gov/articles/PMC11989111/

• Detection Instrument:

  Flow Cytometer