CHI3L1-IN-2

CHI3L1-IN-2

• CAS Number: 2982257-63-4
• UNSPSC Description: CHI3L1-IN-2 (Compound 36) is a CHI3L1(YKL-40) inhibitor. CHI3L1-IN-2 inhibits the interaction between CHI3L1 and heparan sulfate (CHI3L1:HSIII), with an IC50 of 26 nM[1].
• Target Antigen: Others
• Type: Reference compound
• Related Pathways: Others
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/chi3l1-in-2.html
• Solubility: 10 mM in DMSO
• Smiles: CC(C)C[C@H](N(C1)C)CN(C2CCN(C3=CC=CC=N3)CC2)[C@H]1CC4=CC=C(C=C4)Cl
• Molecular Weight: 441.05
• References & Citations: [1]Czestkowski W, et al. Structure-Based Discovery of High-Affinity Small Molecule Ligands and Development of Tool Probes to Study the Role of Chitinase-3-Like Protein 1. J Med Chem. 2024 Mar 14;67(5):3959-3985.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported