CHI3L1-IN-1

CHI3L1-IN-1

• CAS Number: 2982256-78-8
• UNSPSC Description: CHI3L1-IN-1 (Compound 30) is an inhibitor for Chitinase-3-like protein 1 (CHI3L1) (YKL-40) with IC50 of 50 nM. CHI3L1-IN-1 inhibits hERG channel with an IC50 of 2.3 μM[1].
• Target Antigen: Potassium Channel
• Type: Reference compound
• Related Pathways: Membrane Transporter/Ion Channel
• Applications: COVID-19-immunoregulation
• Field of Research: Cancer; Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/chi3l1-in-1.html
• Solubility: DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C)
• Smiles: C[C@H](OC1)CN(C2CCN(C3=CC(Cl)=CC=N3)CC2)[C@H]1CC4=CC=C(C=C4)Cl
• Molecular Weight: 420.38
• References & Citations: [1]Czestkowski W, et al.,Structure-Based Discovery of High-Affinity Small Molecule Ligands and Development of Tool Probes to Study the Role of Chitinase-3-Like Protein 1. J Med Chem. 2024 Mar 14;67(5):3959-3985.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported