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Rel-Erteberel

CAT: 0804-HY-18295A-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-18295A-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rel-Erteberel is rel isomer of Erteberel. Erteberel is a potent and selective estrogen receptor beta (ERβ) agonist with Ki and EC50 of 1.54 nM and 3.61 nM, respectively. Erteberel has anti-tumor activities[1][2].
CAS Number
533883-77-1
Product Name Alternative
Rel-LY500307
UNSPSC
12352005
Target
Estrogen Receptor/ERR
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/rel-erteberel.html
Solubility
10 mM in DMSO
Smiles
OC1=CC=C2O[C@H](C3=CC=C(C=C3)O)[C@@](CCC4)([H])[C@@]4([H])C2=C1
Molecular Formula
C18H18O3
Molecular Weight
282.33
References & Citations
[1]Zhao L, et al. Pharmacological activation of estrogen receptor beta augments innate immunity to suppress cancer metastasis. Proc Natl Acad Sci U S A. 2018 Apr 17;115 (16) :E3673-E3681.|[2]Sareddy GR, et al. Selective Estrogen Receptor β Agonist LY500307 as a Novel Therapeutic Agent for Glioblastoma. Sci Rep. 2016 Apr 29;6:24185.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ERβ

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