(rel) -Oxaliplatin

CAT: 0804-HY-17371ASize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-17371ASize:1 Each
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Description
(rel) -Oxaliplatin is a DNA synthesis inhibitor. (rel) -Oxaliplatin causes DNA crosslinking damage, prevents DNA replication and transcription and induces apoptosis. (rel) -Oxaliplatin can be used for cancer research[1][2][3].
CAS Number
[63121-00-6]
UNSPSC
12352211
Hazard Statement
H315-H317-H319-H335-H351
Target
Apoptosis; DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rel-oxaliplatin.html
Solubility
10 mM in DMSO
Smiles
O=C1[O-][Pt+2]2([O-]C1=O)[NH2][C@@](CCCC3)([H])[C@]3([H])[NH2]2
Molecular Formula
C8H14N2O4Pt
Molecular Weight
397.29
Precautions
P261-P264-P271-P272-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501
References & Citations
[1]Woynarowski JM, et, al. Oxaliplatin-induced damage of cellular DNA. Mol Pharmacol. 2000 Nov;58 (5) :920-7.|[2]Wang Z, et, al. Oxaliplatin induces apoptosis in hepatocellular carcinoma cells and inhibits tumor growth. Expert Opin Investig Drugs. 2009 Nov;18 (11) :1595-604.|[3]Pendyala L, et, al. In vitro cytotoxicity, protein binding, red blood cell partitioning, and biotransformation of oxaliplatin. Cancer Res. 1993 Dec 15;53 (24) :5970-6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched

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