(rel) -Asperparaline A

CAT: 0804-HY-124874Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-124874Size:5 mg
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Description
(rel) -Asperparaline A ((rel) -Aspergillimide), an anthelmintic metabolite, is isolated from okara that has been fermented with Aspergillus japonicas JV-23. (rel) -Asperparaline A is also a potent and selective antagonist of nAChR. (rel) -Asperparaline A exhibits paralytic activity in silk worms[1][2].
CAS Number
[195966-93-9]
Product Name Alternative
(rel) -Aspergillimide; (rel) -VM55598
UNSPSC
12352005
Target
NAChR
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/rel-asperparaline-a.html
Solubility
10 mM in DMSO
Smiles
CN(C1=O)C(C[C@@]2(CC3=O)C(N3C)=O)(CN(CC[C@@H]4C)C14C5)[C@]5([H])C2(C)C.[Rotation(-)]
Molecular Formula
C20H29N3O3
Molecular Weight
359.46
References & Citations
[1]Hayashi H, et, al. New paralytic alkaloids, asperparalines A, B and C, from Aspergillus japonicus JV-23. Biosci Biotechnol Biochem. 2000 Jan;64 (1) :111-5.|[2]Hirata K, et, al. A fungal metabolite asperparaline a strongly and selectively blocks insect nicotinic acetylcholine receptors: the first report on the mode of action. PLoS One. 2011 Apr 1;6 (4) :e18354.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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