Products for Research Use Only
RegisterLogin

Pazopanib (Standard)

CAT: 0804-HY-10208R-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-10208R-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Pazopanib (Standard) is the analytical standard of Pazopanib. This product is intended for research and analytical applications. Pazopanib (GW786034) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRβ, c-Kit, FGFR1, and c-Fms with IC50s of 10, 30, 47, 84, 74, 140 and 146 nM, respectively.
CAS Number
444731-52-6
Product Name Alternative
GW786034 (Standard)
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Autophagy; c-Kit; FGFR; PDGFR; Reference Standards; VEGFR
Type
Reference Standards
Related Pathways
Autophagy; Others; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pazopanib-standard.html
Smiles
O=S(C1=CC(NC2=NC=CC(N(C3=CC4=NN(C(C)=C4C=C3)C)C)=N2)=CC=C1C)(N)=O
Molecular Formula
C21H23N7O2S
Molecular Weight
437.52
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Harris PA, et al. Discovery of 5-[[4-[ (2,3-dimethyl-2H-indazol-6-yl) methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide (Pazopanib), a novel and potent vascular endothelial growth factor receptor inhibitor. J Med Chem. 2008, 51 (15), 4632-4640.|[2]Thakur A, et al. Pazopanib, a multitargeted tyrosine kinase inhibitor, reduces diabetic retinal vascular leukostasis and leakage. Microvasc Res. 2011 Nov;82 (3) :346-50.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

Related Products

CatalogName
HY-12009R-01Pazopanib (Hydrochloride) (Standard)
HY-10208-01Pazopanib
HY-10208S-01Pazopanib-d6
HY-10208S2Pazopanib-d3
HY-12009-01Pazopanib (Hydrochloride)
HY-10208S1Pazopanib-13C, d3
HY-W705479Pazopanib-d3 (hydrochloride)
HY-12009SPazopanib-13C, d3 (hydrochloride)
HY-P2274RArgifin (Standard)
HY-N9362REmodinanthrone (Standard)

Alternative Products

CatalogName
MBS808205-01Pazopanib

Popular Products