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OxLig-1

CAT: 0804-HY-164813-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-164813-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
OxLig-1 (7-Ketocholesteryl-9-carboxynonanoate) is the lipid moiety of oxidized low-density lipoprotein (oxLDL) and is a key ligand for β-glycoprotein I (β (2) -GPI) . oxLig-1 causes nuclear translocation by activating the NF-κB pathway. oxLig-1 can be used in the study of atherosclerosis (AS) [1].
CAS Number
352523-18-3
Product Name Alternative
7-Ketocholesteryl-9-carboxynonanoate
UNSPSC
12352211
Target
NF-κB
Type
Reference compound
Related Pathways
NF-κB
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/oxlig-1.html
Smiles
O=C1[C@]2([H])[C@@](CC[C@]3([C@@]2([H])CC[C@]3([H])[C@H](C)CCCC(C)C)C)([H])[C@@]4(C(C[C@H](CC4)OC(CCCCCCCC(O)=O)=O)=C1)C
Molecular Formula
C36H58O5
Molecular Weight
570.84
References & Citations
[1]Huang Z, et al. 7-ketocholesteryl-9-carboxynonanoate induced nuclear factor-kappa B activation in J774A.1 macrophages. Life Sci. 2010 Nov 20;87 (19-22) :651-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported