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FXIIa-IN-3

CAT: 0804-HY-163347Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-163347Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FXIIa-IN-3 (Compound 8) is a potent and selective Factor XIIa (FXIIa) inhibitor, with an IC50 of 0.045 μM. FXIIa-IN-3 also exhibits a substantial margin of selectivity against related serine proteases, including FXIa, FXa, and FIXa. FXIIa-IN-3 can be used for the research of thromboembolic diseases[1].
UNSPSC
12352005
Target
Factor Xa
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/fxiia-in-3.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=NN(C(C2=CC(OC)=C(OC)C(OC)=C2)=O)C(N)=N1)OC
Molecular Formula
C14H16N4O6
Molecular Weight
336.30
References & Citations
[1]Woodland M L D, et al. New Triazole-Based Potent Inhibitors of Human Factor XIIa as Anticoagulants. ACS Omega. 2024.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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