RA-V

• Description :

  RA-V is a cyclic hexapeptide. RA-V has activity against Wnt, Myc and Notch with IC50 values of 50, 75, and 93 ng/mL, respectively. RA-V can be used for the research of cancer-related signaling pathways[1].

• UNSPSC :

  12352005

• Target :

  C-Myc; Notch; Wnt

• Type :

  Natural Products

• Related Pathways :

  Apoptosis; Neuronal Signaling; Stem Cell/Wnt

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/ra-v.html

• Purity :

  99.85

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  OC1=CC=C2C=C1OC3=CC=C(C[C@@]4(N(C([C@H](C)NC([C@@H](N(C([C@H](C)NC([C@@H](C)NC([C@]([H])(C2)N(C)C4=O)=O)=O)=O)C)CC5=CC=C(OC)C=C5)=O)=O)C)[H])C=C3

• Molecular Formula :

  C40H48N6O9

• Molecular Weight :

  756.84

• References & Citations :

  [1] Premalatha Balachandran, et al. Crosstalk of Cancer Signaling Pathways by Cyclic Hexapeptides and Anthraquinones from Rubia cordifolia. Molecules. 2021 Jan 31;26 (3) :735.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C (Powder, protect from light)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [64725-24-2]