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Bz-rA

CAT: 0804-HY-W008388-01Size: 25 gDry Ice: NoHazardous: No
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CAT#:0804-HY-W008388-01Size:25 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Bz-rA (N6-Benzoyladenosine) is a nucleoside derivative with an N6 protecting group. Bz-rA is mainly used as a synthetic intermediate to participate in photocatalytic oxidative cyclization reactions and synthesize oligoribonucleotides. Bz-rA can be used to efficiently construct heterocyclic skeletons in photochemical conversions and protect the ribose moiety to regulate the cyclization pathway[1][2].
CAS Number
4546-55-8
Product Name Alternative
N6-Benzoyladenosine
UNSPSC
12352005
Hazard Statement
H302
Target
Nucleoside Antimetabolite/Analog
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/bz-ra.html
Purity
99.51
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N2C=NC3=C2N=CN=C3NC(C4=CC=CC=C4)=O
Molecular Formula
C17H17N5O5
Molecular Weight
371.35
Precautions
H302
References & Citations
[1]Shimada K, et al. Oxidative photocyclization of N6-benzoyladenosine derivatives. Facile formation of the quinazolinopurine ring system[J]. Tetrahedron letters, 1987, 28 (2) : 207-210.|[2]Aronoff DM, et al. Cutting edge: macrophage inhibition by cyclic AMP (cAMP) : differential roles of protein kinase A and exchange protein directly activated by cAMP-1. J Immunol. 2005 Jan 15;174 (2) :595-9.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported