Bz-rA

• Description:

  Bz-rA (N6-Benzoyladenosine) is a nucleoside derivative with an N6 protecting group. Bz-rA is mainly used as a synthetic intermediate to participate in photocatalytic oxidative cyclization reactions and synthesize oligoribonucleotides. Bz-rA can be used to efficiently construct heterocyclic skeletons in photochemical conversions and protect the ribose moiety to regulate the cyclization pathway[1][2].

• Product Name Alternative:

  N6-Benzoyladenosine

• UNSPSC:

  12352005

• Hazard Statement:

  H302

• Target:

  Nucleoside Antimetabolite/Analog

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/bz-ra.html

• Purity:

  99.51

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N2C=NC3=C2N=CN=C3NC(C4=CC=CC=C4)=O

• Molecular Formula:

  C17H17N5O5

• Molecular Weight:

  371.35

• Precautions:

  H302

• References & Citations:

  [1]Shimada K, et al. Oxidative photocyclization of N6-benzoyladenosine derivatives. Facile formation of the quinazolinopurine ring system[J]. Tetrahedron letters, 1987, 28 (2) : 207-210.|[2]Aronoff DM, et al. Cutting edge: macrophage inhibition by cyclic AMP (cAMP) : differential roles of protein kinase A and exchange protein directly activated by cAMP-1. J Immunol. 2005 Jan 15;174 (2) :595-9.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [4546-55-8]