RA-PR058

• Description :

  RA-PR058 is an orally active Ramalin derivative with blood-brain barrier permeability, exhibiting multi-target regulatory effects and favorable pharmacokinetic properties. RA-PR058 demonstrates potential as a multi-target modulator for Alzheimer's disease by reducing the expression of BACE1, tau protein hyperphosphorylation, and anxiety-like behaviors[1].

• UNSPSC :

  12352005

• Target :

  Beta-secretase; Tau Protein

• Related Pathways :

  Neuronal Signaling

• Applications :

  Neuroscience-Neurodegeneration

• Field of Research :

  Neurological Disease

• Smiles :

  O=C(NNC1=CC=CC=C1F)CC[C@H](N)C(F)F.Cl

• Molecular Formula :

  C11H15ClF3N3O

• Molecular Weight :

  297.70

• References & Citations :

  [1]Cho Y, et al. RA-PR058, a novel ramalin derivative, reduces BACE1 expression and phosphorylation of tau in Alzheimer's disease mouse models. Anim Cells Syst (Seoul) . 2025 Feb 7;29 (1) :122-134.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported