RA-PR058

CAT: 0804-HY-172176Size: 1 EachDry Ice: NoHazardous: No

CAT#:0804-HY-172176Size:1 Each

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Description

RA-PR058 is an orally active Ramalin derivative with blood-brain barrier permeability, exhibiting multi-target regulatory effects and favorable pharmacokinetic properties. RA-PR058 demonstrates potential as a multi-target modulator for Alzheimer's disease by reducing the expression of BACE1, tau protein hyperphosphorylation, and anxiety-like behaviors[1].

UNSPSC

12352005

Target

Beta-secretase; Tau Protein

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Smiles

O=C(NNC1=CC=CC=C1F)CC[C@H](N)C(F)F.Cl

Molecular Formula

C11H15ClF3N3O

Molecular Weight

297.70

References & Citations

[1]Cho Y, et al. RA-PR058, a novel ramalin derivative, reduces BACE1 expression and phosphorylation of tau in Alzheimer's disease mouse models. Anim Cells Syst (Seoul) . 2025 Feb 7;29 (1) :122-134.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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