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PDE5-IN-9

CAT: 0804-HY-153766-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-153766-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PDE5-IN-9 (Compound 59) is a PDE5 inhibitor (IC50: 11.2 μM) . PDE5-IN-9 shows interaction with Gln 817, Tyr 612, and Ala 767 amino acid residues. PDE5-IN-9 can be used for research of cardiovascular disease[1].
CAS Number
157862-84-5
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/pde5-in-9.html
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C1(C2=CC=CN=C2)=NC(NCC3=CC=CS3)=C4C=CC=CC4=N1
Molecular Formula
C18H14N4S
Molecular Weight
318.40
Precautions
H302, H315, H319
References & Citations
[1]Sarvesh Paliwal, et al. Pharmacophore and molecular docking based identification of novel structurally diverse PDE-5 inhibitors. Medicinal Chemistry Research. 2015, 24, 576-587.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PDE5

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