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PDE5-IN-11

CAT: 0804-HY-149661Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-149661Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PDE5-IN-11 is a potent inhibitor of PDE5 with an IC50 of 40 nM. PDE5-IN-11 also inhibits PDE4 and PDE6 with IC50s of 1.78 and 0.09 μM, respectively[1].
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/pde5-in-11.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=C(CNC2=C3C(N(C(C)C)C(N3)=O)=NC(N(CCO)CCO)=N2)C=C1
Molecular Formula
C20H28N6O4
Molecular Weight
416.47
References & Citations
[1]Jiayuan Liu, et al. Drug repurposing and structure-based discovery of new PDE4 and PDE5 inhibitors, European Journal of Medicinal Chemistry (2023) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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