PDE5-IN-11

PDE5-IN-11

• UNSPSC Description: PDE5-IN-11 is a potent inhibitor of PDE5 with an IC50 of 40 nM. PDE5-IN-11 also inhibits PDE4 and PDE6 with IC50s of 1.78 and 0.09 μM, respectively[1].
• Target Antigen: Phosphodiesterase (PDE)
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Neuroscience-Neuromodulation
• Field of Research: Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/pde5-in-11.html
• Solubility: 10 mM in DMSO
• Smiles: COC1=CC=C(CNC2=C3C(N(C(C)C)C(N3)=O)=NC(N(CCO)CCO)=N2)C=C1
• Molecular Weight: 416.47
• References & Citations: [1]Jiayuan Liu, et al. Drug repurposing and structure-based discovery of new PDE4 and PDE5 inhibitors, European Journal of Medicinal Chemistry (2023).
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported