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Myristicin

CAT: 0804-HY-N2510-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N2510-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Myristicine is an orally bioavailable serotonin receptor antagonist and weak monoamine oxidase (MAO) inhibitor. Myristicine also exerts anti-cancer effects on gastric cancer cells by inhibiting the EGFR/ERK signaling pathway. Myristicine is the main component of nutmeg essential oil and has anti-cancer, anti-proliferative, antibacterial, anti-inflammatory and apoptosis-inducing effects. Myristicine abuse can produce hallucinogenic effects, organ damage, etc[1][2][3][4].
CAS Number
607-91-0
Product Name Alternative
Myristicine
UNSPSC
12352005
Hazard Statement
H361, H412
Target
5-HT Receptor; Apoptosis; Bacterial; EGFR; ERK
Type
Natural Products
Related Pathways
Anti-infection; Apoptosis; GPCR/G Protein; JAK/STAT Signaling; MAPK/ERK Pathway; Neuronal Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Applications
Neuroscience-Neuromodulation
Field of Research
Cancer; Infection; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/myristicin.html
Purity
99.89
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C=CCC1=CC(OC)=C2OCOC2=C1
Molecular Formula
C11H12O3
Molecular Weight
192.21
Precautions
H361, H412
References & Citations
[1]Kalbhen DA, et al. Nutmeg as a narcotic. A contribution to the chemistry and pharmacology of nutmeg (Myristica fragrans) .Angew Chem Int Ed Engl. 1971 Jun;10 (6) :370-4.|[2]Dawidowicz AL, et al. Simple and rapid determination of myristicin in human serum.Forensic Toxicol. 2013 Jan;31 (1) :119-123. Epub 2012 Aug 15.|[3]Badr G, Elsawy H, Amalki M A, et al. Protective effects of myristicin against ulcerative colitis induced by acetic acid in male mice[J]. Food and Agricultural Immunology, 2020, 31 (1) : 435-446.|[4]Song J, et al. Myristicin Suppresses Gastric Cancer Growth via Targeting the EGFR/ ERK Signaling Pathway. Curr Mol Pharmacol. 2023;16 (7) :712-724.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
EGFR/ErbB1/HER1; ERK

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Alternative Products

CatalogName
BA1329-5.1Myristicin
AB0452Myristicin Aldehyde
sc-477764Myristicin Acid Methyl Ester
017931Myristicin discontinued. See 282982

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