Myristic acid

• Description:

  Myristic acid is an orally active saturated 14-carbon fatty acid found in most animal and plant fats, especially milk fat coconut oil, palm oil and nutmeg oil. Myristic acid exerts anti-inflammatory activity through the NF-κB pathway. Myristic acid has antibacterial, anti-inflammatory and analgesic properties[1][2][3][4].

• UNSPSC:

  12352211

• Hazard Statement:

  H319

• Target:

  Bacterial; Endogenous Metabolite; NF-κB

• Type:

  Natural Products

• Related Pathways:

  Anti-infection; Metabolic Enzyme/Protease; NF-κB

• Field of Research:

  Infection; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/Myristic_acid.html

• Purity:

  99.88

• Solubility:

  DMSO : 200 mg/mL (ultrasonic) |Ethanol : 100 mg/mL (ultrasonic)

• Smiles:

  CCCCCCCCCCCCCC(O)=O

• Molecular Formula:

  C14H28O2

• Molecular Weight:

  228.37

• Precautions:

  H319

• References & Citations:

  [1]Hu M, et al. Myristic acid regulates triglyceride production in bovine mammary epithelial cells through the ubiquitination pathway. Agriculture, 2023, 13 (10) : 1870.|[2]Oepen K, et al. Myristic Acid Inhibits the Activity of the Bacterial ABC Transporter BmrA. Int J Mol Sci. 2021 Dec 17;22 (24) :13565.|[3]Alonso-Castro AJ, et al. Myristic acid reduces skin inflammation and nociception. J Food Biochem. 2022 Jan;46 (1) :e14013.|[4]Huang Q, et al. Anti-inflammatory effects of myristic acid mediated by the NF-κB pathway in lipopolysaccharide-induced BV-2 microglial cells. Mol Omics. 2023 Oct 30;19 (9) :726-734.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  Store at room temperature 3 years

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• Isoform:

  Human Endogenous Metabolite

• CAS Number:

  [544-63-8]