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WWOX Polyclonal Antibody

CAT: 0965-JOT-AP09607-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP09607-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
WWOX (WW domain containing oxidoreductase) encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. WWOX spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene. Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated with multiple types of cancer. Disruption of WWOX is also associated with autosomal recessive spinocerebellar ataxia 12. Disruption of a similar gene in mouse results in impaired steroidogenesis, additionally suggesting a metabolic function for the protein. Alternative splicing results in multiple transcript variants.
CAS Number
9007-83-4
Synonyms
WWOX; FOR; WOX1; WW domain-containing oxidoreductase; Fragile site FRA16D oxidoreductase
Host
Rabbit
Reactivity
Human;Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human WWOX. AA range:1-50
Clonality
Polyclonal
Applications
WB, IHC-p, IF, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
46677
Antibody Type
Primary antibody
Isotype
IgG

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