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WWTR1 Polyclonal Antibody

CAT: 0965-JOT-AP15563-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP15563-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Binds to transcription factors via its WW domain.,The PDZ-binding motif is essential for stimulated gene transcription. It localizes the protein into both punctate nuclear foci and plasma membrane-associated complexes.,Functions as a transcriptional coactivator.,PTM:Phosphorylated. Phosphorylation results in the inhibition of transcriptional coactivation through YWHAZ-mediated nuclear export.,Contains 1 WW domain.,subcellular location:Concentrates along specific portions of the plasma membrane, and accumulates in punctate nuclear bodies. When phosphorylated, is retained in cytoplasm by YWHAZ.,subunit:Binds to SLC9A3R2 via the PDZ motif at the plasma membrane. Binds to YWHAZ in vivo and in vitro through the phosphoserine-binding motif RSHSSP.,tissue specificity:Highly expressed in kidney, heart, placenta and lung.,
CAS Number
9007-83-4
Synonyms
WW domain-containing transcription regulator protein 1 ;Transcriptional coactivator with PDZ-binding motif
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Antibody Type
Primary antibody
Isotype
IgG

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