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Rad51B Polyclonal Antibody

CAT: 0965-JOT-AP07609-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP07609-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by RAD51B (RAD51 paralog B) is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of RAD51B was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata.
CAS Number
9007-83-4
Synonyms
RAD51B; RAD51L1; REC2; DNA repair protein RAD51 homolog 2; R51H2; RAD51 homolog B; Rad51B; RAD51-like protein 1
Host
Rabbit
Reactivity
Human;Mouse;Monkey
Immunogen
The antiserum was produced against synthesized peptide derived from human RAD51L1. AA range:201-250
Clonality
Polyclonal
Applications
WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
42196
Antibody Type
Primary antibody
Isotype
IgG

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