Products for Research Use Only
RegisterLogin

Rad17 Polyclonal Antibody

CAT: 0965-JOT-AP07600-01Size: 20 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0965-JOT-AP07600-01Size:20 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The protein encoded by RAD17 (RAD17 checkpoint clamp loader component) is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation. The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest, and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells. Multiple alternatively spliced transcript variants of this gene, which encode four distinct protein isoforms, have been reported. Two pseudogenes, located on chromosomes 7 and 13, have been identified.
CAS Number
9007-83-4
Synonyms
RAD17; R24L; Cell cycle checkpoint protein RAD17; hRad17; RF-C/activator 1 homolog
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
Synthesized peptide derived from Rad17 . at AA range: 580-660
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
77055
Antibody Type
Primary antibody
Isotype
IgG

Related Products

CatalogName
JOT-AP13500-01Rad17(Phospho Ser645) Polyclonal Antibody
JOT-AP13501-01Rad17(Phospho Ser646) Polyclonal Antibody
JOT-AP12226-01Rad17(Phospho-Ser635) Rabbit Polyclonal Antibody
JOT-AP07602-01Rad18 Polyclonal Antibody
JOT-AP13499-01RAD1 Polyclonal Antibody
JOT-AP13498-01RAD1 Polyclonal Antibody
JOT-AP12227-01Rad18(Phospho-Ser403) Rabbit Polyclonal Antibody
JOT-AP01329-01CD10 Polyclonal Antibody
JOT-AP01765-01Chk1 Polyclonal Antibody
JOT-AP01456-01CD300d Polyclonal Antibody

Alternative Products

CatalogName
ABP-PAB-10132RAD17 homolog (RAD17) polyclonal antibody
MBS2542403-01RAD17 Polyclonal Antibody
APR00113GPolyclonal Rad17 Antibody

Popular Products