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Rad18 Polyclonal Antibody

CAT: 0965-JOT-AP07602-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP07602-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
RAD18, E3 ubiquitin protein ligase encoded by RAD18 is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, RAD18, E3 ubiquitin protein ligase is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.
CAS Number
9007-83-4
Synonyms
RAD18; RNF73; E3 ubiquitin-protein ligase RAD18; Postreplication repair protein RAD18; hHR18; hRAD18; RING finger protein 73
Host
Rabbit
Reactivity
Human;Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human RAD18. AA range:301-350
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
56195
Antibody Type
Primary antibody
Isotype
IgG

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