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Nodal Polyclonal Antibody

CAT: 0965-JOT-AP06091-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP06091-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
NODAL (nodal growth differentiation factor) encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which regulates early embryonic development. This protein is required for maintenance of human embryonic stem cell pluripotency and may play a role in human placental development. Mutations in NODAL are associated with heterotaxy, a condition characterized by random orientation of visceral organs with respect to the left-right axis.
CAS Number
9007-83-4
Synonyms
NODAL; Nodal homolog
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
The antiserum was produced against synthesized peptide derived from the C-terminal region of human NODAL. AA range:294-343
Clonality
Polyclonal
Applications
WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
39561
Antibody Type
Primary antibody
Isotype
IgG

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