CD14 Protein

CAT: 0384-NCP0176-01Size: 500 µgDry Ice: NoHazardous: No
CAT#:0384-NCP0176-01Size:500 µg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CD14 is a leucine-rich repeat-containing pattern recognition receptor with expression largely restricted to the monocyte/macrophage cell lineage. Research studies have shown that CD14 is a bacterial lipopolysaccharide (LPS) binding glycoprotein, expressed as either a GPI-linked membrane protein or a soluble plasma protein. LPS induces an upregulation of GPI-linked CD14 expression, which facilitates TLR4 signaling and macrophage activation in response to bacterial infection. The 61D3 antibody is widely used to identify cells of the monocyte/macrophage lineage.
Swiss Prot
P08571
Modification Site
NdeI-XhoI
Expression System
Pet-22b (+)
Tag
His-tag
Purity
Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE) .
Solubility
PBS, 4M Urea, PH7.4
Molecular Weight
~40kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Host or Source
E.coli
AA Sequence
ACCACCCCTGAACCGTGCGAACTGGATGATGAAGACTTCCGCTGCGTGTGTAACTTCAGTGAACCGCAGCCGGATTGGAGCGAAGCCTTCCAGTGCGTTAGTGCAGTTGAAGTGGAAATTCATGCAGGCGGCCTGAATCTGGAACCGTTCCTGAAACGCGTTGATGCAGATGCAGATCCGCGCCAGTATGCCGATACCGTTAAAGCCCTGCGTGTGCGTCGTCTGACCGTGGGTGCAGCACAGGTGCCGGCACAGCTGCTGGTTGGTGCACTGCGTGTTCTGGCCTATAGTCGCCTGAAAGAACTGACCCTGGAAGATCTGAAAATTACCGGTACCATGCCGCCGCTGCCGCTGGAAGCCACCGGTCTTGCACTGAGCAGCCTGCGTCTGCGTAATGTGAGCTGGGCCACCGGTCGCAGCTGGCTGGCAGAACTGCAGCAGTGGCTGAAACCGGGTCTGAAAGTTCTGAGCATTGCCCAGGCACATAGCCCGGCATTCAGTTGCGAACAGGTTCGCGCCTTCCCGGCACTGACCAGTCTGGATCTGAGTGATAATCCGGGTCTGGGCGAACGCGGTCTGATGGCCGCACTGTGTCCGCATAAATTCCCGGCAATTCAGAATCTGGCACTGCGTAATACCGGTATGGAAACACCTACCGGTGTGTGTGCAGCCCTGGCCGCCGCTGGTGTGCAGCCTCATAGCCTGGATCTGTCACATAATAGCCTGCGCGCCACCGTTAATCCGAGCGCCCCGCGTTGCATGTGGAGCAGCGCACTGAATAGCCTGAATCTGAGCTTCGCAGGTCTGGAACAGGTTCCGAAAGGCCTGCCGGCAAAACTGCGTGTTCTTGATCTGAGCTGTAATCGCCTGAATCGCGCACCGCAGCCGGACGAACTGCCGGAAGTGGATAATCTGACCCTGGATGGTAATCCGTTCCTGGTGCCGGGCACCGCACTGCCTCATGAAGGCAGCATGAAT

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