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CD14 monoclonal antibody

CAT: 0384-MB66024-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-MB66024-01Size:50 µL
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Background
CD14 is a leucine-rich repeat-containing pattern recognition receptor with expression largely restricted to the monocyte/macrophage cell lineage. Research studies have shown that CD14 is a bacterial lipopolysaccharide (LPS) binding glycoprotein, expressed as either a GPI-linked membrane protein or a soluble plasma protein. LPS induces an upregulation of GPI-linked CD14 expression, which facilitates TLR4 signaling and macrophage activation in response to bacterial infection.
CAS Number
9007-83-4
Structure Composition
Mouse IgG2b. Liquid in PBS containing 50% glycerol, 0.2% BSA and 0.01% sodium azide.
Product Name Alternative
Monocyte differentiation antigen CD14; Myeloid cell-specific leucine-rich glycoprotein; CD14
Swiss Prot
P08571
Reactivity
Human
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within human CD14. The exact sequence is proprietary.
Conjugation
Unconjugated
Applications
IHC
Dilution
IHC (1/100 - 1/300)
Purity
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 40 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Recognizes endogenous levels of CD14 protein.
Host or Source
Mouse

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