CIDEA polyclonal antibody

• Background:

  This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified.

• Structure Composition:

  Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative:

  CIDEA; CIDE-A

• Swiss Prot:

  O60543

• Reactivity:

  Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human CIDEA (NP_001270.1) .

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC-P

• Dilution:

  WB: 1:500~1:1000 IHC: 1:50~1:200

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification:

  Unmodified

• Molecular Weight:

  ~ 25 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  CIDEA polyclonal antibody detects endogenous levels of CIDEA protein.

• Applications Notes:

  Western blot analysis of lysates from Mouse heart, using CIDEA pAb at 1:1000 dilution.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4