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OAZ3 polyclonal antibody

CAT: 0384-BS60197-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS60197-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The antizyme family is a group of small proteins that play a role in cell growth and division by regulating the biosynthesis of polyamines such as putrescine, spermidine and spermine. AZ3, also known as OAZ3 (Ornithine decarboxylase antizyme 3), is a 187 amino acid protein that belongs to the ODC antizyme family. AZ3 probably plays a key role in spermatogenesis by regulating the intracellular concentration of polyamines in haploid germ cells because it binds to, and destabilizes, ornithine decarboxylase. However, mutations in the AZ3 gene are not a common cause of male infertility and the normal AZ3 protein does not accelerate ornithine decarboxylase degeneration. AZ3 expression has a sharp onset in early spermatids, peaks in later stages and is gone in spermatozoa.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Ornithine decarboxylase antizyme 3; AZ3; ODC-Az 3
Swiss Prot
Q9UMX2
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human OAZ3.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 21 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
OAZ3 polyclonal antibody detects endogenous levels of OAZ3 protein.
Applications Notes
Western blot (WB) analysis of OAZ3 polyclonal antibody at 1:500 dilution Lane1:Jurkat whole cell lysate Lane2:Mouse testis tissue lysate Lane3:Rat testis tissue lysate
Host or Source
Rabbit

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