Products for Research Use Only

TADA2L polyclonal antibody

CAT: 0384-BS5953-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS5953-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TADA2L (transcriptional adapter 2-like), also known as TADA2A (transcriptional adapter 2-α) or ADA2-like protein, is a 443 amino acid nuclear protein that exists as 2 alternatively spliced isoforms. While most abundantly expressed in testis, TADA2L is present in all tissues. TADA2L contains one SANT domain and one SWIRM domain, and interacts with GCN5 and GR (NR3C1) . Its ability to bind double-stranded DNA allows TADA2L to play a role in chromatin remodeling. Although it makes up part of the PCAF complex, TADA2L is also a component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. The gene that encodes TADA2L contains 71,408 bases and maps to human chromosome 17q12. Chromosome 7 houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to osteogenesis imperfecta, Pendred syndrome, lissencephaly, citrullinemia and Shwachman-Diamond syndrome.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Transcriptional adapter 2-alpha; Transcriptional adapter 2-like; ADA2-like protein; TADA2A; TADA2L; KL04P
Swiss Prot
O75478
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 248-293 of Human TADA2L.
Conjugation
Unconjugated
Applications
WB ICC
Dilution
WB: 1:500~1:1000 ICC: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 51 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
TADA2L polyclonal antibody detects endogenous levels of TADA2L protein.
Applications Notes
Western blot (WB) analysis of TADA2L polyclonal antibody at 1:500 dilution Lane1:MCF-7 cell lysate Lane2:sp2/0 cell lysate Lane3:H9C2 cell lysate
Host or Source
Rabbit