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LIPC polyclonal antibody

CAT: 0384-BS5756-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS5756-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The Lipase family belongs to one of the most robust genetic superfamilies found in living organisms that includes esterases and thioesterases. Lipase gene products are related by tertiary structure rather than primary amino acid sequence. Balancing the composition and the transport of lipoproteins in human plasma is essential for normal body function and is mediated in part by Hepatic Lipase, also known as HL or LIPC. Rare deficiencies in Hepatic Lipase have been identified in humans which lead to pathologic levels of circulating lipoprotein particles; this condition is associated with coronary artery disease (CAD) . Hepatic Lipase is regulated by thyroid hormones and has a dual function as a triglyceride hydrolase and a ligand/bridging factor for receptor-mediated lipoprotein uptake. Hepatic Lipase localizes to the endothelial surfaces of extrahepatic tissues.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Hepatic triacylglycerol lipase; Short name=HL; Hepatic lipase; Lipase member C; LIPC; HTGL
Swiss Prot
P11150
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to the 349-394 of Human LIPC.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 56 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
LIPC polyclonal antibody detects endogenous levels of LIPC protein.
Applications Notes
Western blot (WB) analysis of LIPC polyclonal antibody at 1:500 dilution Lane1:HEK293T cell lysate Lane2:NIH-3T3 cell lysate Lane3:H9C2 cell lysate
Host or Source
Rabbit