BCAS2 polyclonal antibody

CAT: 0384-BS5626-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-BS5626-01Size:50 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
BCAS2 (breast carcinoma amplified sequence 2), also designated DAM1 (DNA amplified in mammary carcinoma 1 protein) or spliceosome-associated SPF 27, is a ubiquitously expressed nuclear protein that was originally identified as being overexpressed in various breast cancer cell lines. BCAS2 is now known to be a component of the spliceosome, participating in the removal of introns from mRNA precursors. BCAS2 specifically interacts (in a ligandindependent manner) with TRβ (thyroid hormone receptor β), ERα (estrogen receptor α), ERβ, PR (progesterone receptor), and PPARγ (Peroxisome proliferator-activated receptor γ) . BCAS2 functions as an ER coactivator and is capable of enhancing ER-mediated transcription. This suggests that BCAS2 is involved in the development of breast cancer.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Pre-mRNA-splicing factor SPF27; Breast carcinoma-amplified sequence 2; DNA amplified in mammary carcinoma 1 protein; Spliceosome-associated protein SPF 27; DAM1
Swiss Prot
O75934
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 180-225 of Human BCAS2.
Conjugation
Unconjugated
Applications
WB ICC IP
Dilution
WB: 1:500~1:1000 ICC: 1:50~1:200 IP: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 26 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
BCAS2 polyclonal antibody detects endogenous levels of BCAS2 protein.
Applications Notes
Western blot (WB) analysis of BCAS2 polyclonal antibody at 1:500 dilution Lane1:HEK293T cell lysate Lane2:Mouse heart tissue lysate Lane3:PC12 cell lysate
Host or Source
Rabbit

Related Products

CatalogName
BS47922-01BCAS2 Recombinant Rabbit mAb
BS62320-01BCAS3 polyclonal antibody
BS8888-01BCAT2 polyclonal antibody
BS61537BCAS3 polyclonal antibody
BS8802-01BCAS3 polyclonal antibody
BZ16794-01Polyclonal antibodyPN1 polyclonal antibody
BS74827-01KMT2A polyclonal antibody
BS78111Lyn polyclonal antibody
BS78087-01PIK3IP1 polyclonal antibody
BS8359-01PLA2G2D polyclonal antibody

Alternative Products

CatalogName
MBS2540880-01BCAS2 Polyclonal Antibody
TA345935BCAS2 Rabbit Polyclonal Antibody
NB110-40681Rabbit Polyclonal BCAS2 Antibody

Popular Products