BCAS3 polyclonal antibody

• Background:

  Plays a role in angiogenesis. Participates in the regulation of cell polarity and directional endothelial cell migration by mediating both the activation and recruitment of CDC42 and the reorganization of the actin cytoskeleton at the cell leading edge. Promotes filipodia formation (By similarity) . Functions synergistically with PELP1 as a transcriptional coactivator of estrogen receptor-responsive genes. Stimulates histone acetyltransferase activity. Binds to chromatin.

• Structure Composition:

  Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative:

  Breast carcinoma-amplified sequence 3; GAOB1; BCAS3

• Swiss Prot:

  Q9H6U6

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant full length Human BCAS3.

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC, IF

• Dilution:

  WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification:

  Unmodification

• Molecular Weight:

  ~ 115 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  BCAS3 polyclonal antibody detects endogenous levels of BCAS3 protein.

• Applications Notes:

  Western blot analysis of extracts of various cell lines, using BCAS3 antibody.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4