Products for Research Use Only
RegisterLogin

PPAR-γ (I106) polyclonal antibody

CAT: 0384-BS1587-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0384-BS1587-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
PPAR gamma is implicated in numerous diseases including obesity, diabetes, atherosclerosis and cancer. PPAR gamma activators include prostanoids, fatty acids, thiazolidinediones and N- (2-benzoylphenyl) tyrosine analogues. A key component in adipocyte differentiation and fat-specific gene expression, PPAR gamma may modulate macrophage functions such as proinflammatory activities, and stimulate oxidized low-density lipoprotein (x-LDL) uptake. A Pro12Ala polymorphism of the PPAR gamma2 gene has been reported to reduce transactivation activity in vitro. This substitution may affect the immune response to ox-LDL and be associated with type 2 diabetes. In addition, the Pro12Ala variant of the PPAR gamma2 gene maybe correlated with abdominal obesity in type 2 diabetes.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Peroxisome proliferator-activated receptor gamma; Short name=PPAR-gamma; Nuclear receptor subfamily 1 group C member 3; PPARG; NR1C3; PPAR γ; PPARγ
Swiss Prot
P37231
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 90-120 of Human PPAR-γ.
Conjugation
Unconjugated
Related Pathways
Nuclear Receptor Signaling, MTOR signaling
Applications
WB IHC
Dilution
WB: 1:500~1:1000 IHC: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 54 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
PPAR-γ (I106) polyclonal antibody detects endogenous levels of PPAR-γ protein .
Applications Notes
Western blot (WB) analysis of PPAR-γ (I106) polyclonal antibody at 1:500 dilution Lane1:MEF whole cell lysate (40ug) Lane2:A549 whole cell lysate (40ug) Lane3:PC12 whole cell lysate (40ug) Lane4:L02 whole cell lysate (40ug)
Host or Source
Rabbit

Related Products

CatalogName
BS2032-01CREM (I106) polyclonal antibody
BS1413-01Bad (I106) polyclonal antibody
BS91100PPARγ polyclonal antibody
BS6442PPARγ polyclonal antibody
GCP114-01PPARβ polyclonal antibody
BS91101PPARγ polyclonal antibody
BS79617-01PPARγ polyclonal antibody
AP0606-01PPARγ (S112) polyclonal antibody
AP0659PPAR-gama polyclonal antibody
AP0686PPAR-γ (K160) polyclonal antibody

Alternative Products

CatalogName
E43S1587PPAR-γ (I106) polyclonal antibody
GTR18041619-01CREM (I106) polyclonal antibody
GTR18041225-01Bad (I106) polyclonal antibody
ABP55667-01PPAR-α Polyclonal Antibody
ABP52252-01PPAR-γ Polyclonal Antibody
GTR18049330-01PPARβ polyclonal antibody
GTR18044760-01PPARγ polyclonal antibody
MBS8519623-01PPAR-gamma Polyclonal Antibody
A04379Anti-CREM (I106) Antibody

Popular Products